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已有 590 次阅读2010-9-27 09:32 |

Results: after three around observation fight n/med tuberculosis medicaments drug resistance. Conclusion: DPC is a kind of independent of anti-tuberculosis drugs are effective for drug-resistant TB, but in 1 g concentration is still close 30% growth, think there should double.[key] : Dipasic resistanceThe thesis] : anti-tuberculosis medication use, in the landmark on TB control. In the 1950s by INH + moncler PAS combination therapy, and achieved good effect. But, gastrointestinal reaction PAS dose, patients cannot tolerate, 90% cannot complete treatment process. Switzerland Geistlich pharmaceutical development Dipasic (hereinafter referred to as DPC) (Germany), is GEWO399 and special methods, synthetic compounds with PAS INH. It can replace INH + PAS, add curative effects, for less than a PAS Freudenthal Germany as 50 experts moncler jackets have Dipasic clinical application report that effectively. But no reports of Dipasic resistance. Currently, China's resistance increases, the patient is urgent for rational drug use, we Dipasic to do research purpose, patience, (1) to understand Dipasic drug-resistant valid? (2) Dipasic drug inhibitory concentration? To study and usage, improve the clinical curative effect. 1, research methods: from anhui medical university hospital moncler vest outpatient service and ward tuberculosis patient phlegm for training, whether patients with tuberculosis concomitant suppression is treated first, men and women, old and young, all who phlegm, cultivate positive as the research object. According to the standard of n/med tuberculosis bacterium, routine operations. Drug preparation of media: liquid medium eggs, proportional to join the fight n/med tuberculosis medicaments, according to moncler coats Chinese standard of drug concentrations, such as INH, TB1, every milliliter PAS, respectively (1 g and 10 mu g speeds, SM, 10 KM, CPM respectively, and RFD muon g RFPS for 50 mu g and 250 g, EMB for 5 speeds and 50 mu g muon g. Dipasic is temporary per milliliter medicated 0.1 muon g, 0.5 muon g, 1.0 Cheap Moncler muon g and 10 mu g four. After joining drugs, shake the mixing tube, each packing in the test tube 5 ml, cant, 85-90 degrees for an hour, 24 hours after sterilization of solidification once again made of sterilization, medicine, save in the refrigerator, medium within a month. Microbial preparation: medium in the colonies, within one month of the growth Discount Moncler of bacteria in sterilized saline grinding homogeneously bacterium fluid, add salt diluted with standard, the sterilizer is made every milliliter (tube containing 1 ml of microbial), and the last 100 times diluted into every milliliter containing 10-2 mg bacterium fluid back-up. Microbial inoculated with different concentration: medium containing medicines, and have no order as the medium containing drugs. Take every Moncler Outlet milliliter containing 10-2 mg per pipe bacteria, fungi, vaccination 0.1 ml of 10-3 mg of bacteria. In 37 degrees Celsius temperature cabinet, watching a weekly report, around. The report is medium, such as the standard for the growth of aseptic (1), the number of bacterial culture is in 50 below for (+), the number of bacterial culture, but no more Moncler Sale than 50 for fusion (+ +), medium for fusion in most colonies (+ + +). 2, the results of the study of 10: we fight n/med tuberculosis medicaments resistance test, the 10 kinds of anti-tuberculosis drugs are: INH, PAS, DPC, TB1 EMB, RFD, SM, RFP, KM and a CPM, and this purpose, we only around 30 patients, including INH PAS

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